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Influence of stationary phase properties on the separation of ionic liquid cations by RP‐HPLC
Author(s) -
Buszewski Bogusław,
Kowalska Sylwia,
Stepnowski Piotr
Publication year - 2006
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200500358
Subject(s) - chemistry , ionic liquid , alkyl , protonation , high performance liquid chromatography , chromatography , stationary phase , phase (matter) , ionic bonding , organic chemistry , ion , catalysis
Different types of columns with specific structural properties were used for the separation of mixtures of ionic liquid cations. Two of them were home‐made packings and the other two were commercial stationary phases. One of the home‐made packings contained cholesterol ligands bonded chemically to silica (SG‐CHOL) whereas the other one was a mixed stationary phase (SG‐MIX) with cyanopropyl, aminopropyl, phenyl, octyl, and octadecyl ligands. RP‐18e Innovation ChromolithTM Performance and Macrosphere 300 C4 packings were also used. A comparison of the separation possibilities offered by these columns for the substances in question revealed significant differences in performance. Packings containing surface‐bonded functional groups that are able to undergo protonation are not suitable for separation of such compounds under the given analysis conditions (pH = 4). The best results were obtained for two alkyl stationary phases: butyl and octadecyl. Cluster analysis has also been performed for comparison of the ionic liquid cation properties.