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Selective enrichment of anti‐inflammatory drugs from river water samples by solid‐phase extraction with a molecularly imprinted polymer
Author(s) -
Caro Ester,
Marcé Rosa M.,
Cormack Peter A. G.,
Sherrington David C.,
Borrull Francesc
Publication year - 2005
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200500027
Subject(s) - molecularly imprinted polymer , sorbent , solid phase extraction , chromatography , dichloromethane , chemistry , molecular imprinting , extraction (chemistry) , polymer , naproxen , aqueous solution , solvent , adsorption , organic chemistry , selectivity , medicine , alternative medicine , pathology , catalysis
A molecularly imprinted polymer (MIP) is synthesised by a noncovalent protocol in which ibuprofen was used as a template molecule. The polymer was evaluated chromatographically and it was seen that the MIP showed cross‐reactivity. Subsequently, when this polymer was used as sorbent in SPE it was possible to selectively extract a mixture of nonsteroidal anti‐inflammatory drugs from aqueous samples when a clean‐up step with dichloromethane was performed. The performance of the MIP was evaluated with river water and water from a wastewater treatment plant, and compared with the performance of a commercial Isolute ENV+ sorbent.