Premium
Application of naphthylcarbamate‐substituted β‐cyclodextrin bonded silica particles as stationary phase for high‐performance liquid chromatography
Author(s) -
Gong Yinhan,
Lee Hian Kee
Publication year - 2003
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200390069
Subject(s) - enantiomer , chemistry , cyclodextrin , high performance liquid chromatography , chromatography , selectivity , silica gel , phase (matter) , chiral column chromatography , structural isomer , stationary phase , chiral stationary phase , organic chemistry , catalysis
Naphthylcarbamate‐substituted (3‐(2‐O‐β‐cyclodextrin)‐2‐hydroxypropoxy)‐propylsilyl‐appended silica gel (NSCD‐HPS) has been synthesized via a convenient liquid‐solid phase reaction on a silica gel surface. The chromatographic behavior of NSCD‐HPS in high‐performance liquid chromatography (HPLC) was studied with several disubstituted benzenes and some chiral aromatic compounds under both normal and reversed‐phase conditions. The results show that NSCD‐HPS has excellent selectivity for the separation of positional isomers of disubstituted benzenes and enantiomers of chiral aromatic compounds.