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Direct resolution of novel tetrahedral metal clusters on a cellulose tris‐(3,5‐dimethylphenylcarbamate) chiral stationary phase by high‐performance liquid chromatography
Author(s) -
Zhu Xinyi,
Cai Yingchun,
Zhang Weiqiang,
Chen Liren,
Li Yongmin
Publication year - 2003
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200301522
Subject(s) - enantiomer , chemistry , cellulose , phase (matter) , tris , resolution (logic) , high performance liquid chromatography , chromatography , chiral column chromatography , tetrahedron , hexane , analytical chemistry (journal) , organic chemistry , crystallography , biochemistry , artificial intelligence , computer science
Direct optical resolution of five novel tetrahedral heterometal cluster enantiomers has been achieved for the first time on a cellulose tris‐(3,5‐dimethylphenylcarbamate) chiral stationary phase, using hexane as the mobile phase with various alcohols as modifiers. UV detection was carried out at 254 nm. The influence of the mobile phase composition on enantioselectivity is discussed and optimum resolution has been achieved. The effect of structural variation of the solutes on their enantioseparation has also been investigated.