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Fast comprehensive two‐dimensional gas chromatography (GC×GC) using 50‐μm ID second‐dimension columns
Author(s) -
Adahchour Mohamed,
Tas̨öz Ayla,
Beens Jan,
Vreuls René J. J.,
Batenburg A. Max,
Brinkman Udo A. Th.
Publication year - 2003
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/jssc.200301332
Subject(s) - dimension (graph theory) , two dimensional gas , gas chromatography , chromatography , two dimensional chromatography , column (typography) , resolution (logic) , chemistry , analytical chemistry (journal) , mathematics , computer science , artificial intelligence , combinatorics , geometry , connection (principal bundle)
Up till now, comprehensive two‐dimensional gas chromatography has suffered from the serious disadvantage that the first‐dimension separation has to be operated both at sub‐optimum flow and at slow temperature programming rates to enable the required number of modulations across a first‐dimension peak. Consequently, the separation efficiency of the first‐dimension is (far) below optimum and the overall analysis times become longer than necessary. This problem can be solved by selecting a short 50‐μm ID second‐dimension column, and combining it with a standard long 250‐μm ID first‐dimension column. Compared with conventional GC×GC set‐ups, an over 3‐fold reduction of the analysis time was reached in the present study without sacrificing resolution; to the contrary, a substantial increase of the peak capacity was obtained.