Open AccessThe chondrodystrophic dog: A clinically relevant intermediate‐sized animal model for the study of intervertebral disc‐associated spinal pain
Author(s) -
Thompson Kelly,
Moore Sarah,
Tang Shirley,
Wiet Matthew,
Purmessur Devina
Publication year - 2018
Publication title -
jor spine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2572-1143
DOI - 10.1002/jsp2.1011
Subject(s) - medicine , intervertebral disc , low back pain , animal model , population , pathological , back pain , translational research , pathology , surgery , alternative medicine , environmental health
This review paper highlights the use of clinically relevant intermediate‐sized animal models for the study of intervertebral disc‐associated back pain with an emphasis on the chondrodystrophic dog population. While making comparisons across species we review studies to date that have characterized this species as a model for studying the disc including studies that have assessed therapeutic strategies.