Premium
Sinus histiocytosis mimicking metastatic melanoma in lymph nodes of a patient with a large joint prosthesis: Case report and review of the literature
Author(s) -
Charny Caleb K.,
Jacobowitz Glenn,
Melamed Jonathan,
Tata Mona,
Harris Matthew N.
Publication year - 1995
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930600212
Subject(s) - medicine , melanoma , lymph , lymph node , prosthesis , sinus (botany) , dissection (medical) , radiology , histiocytosis , metastatic melanoma , pathology , surgery , disease , botany , cancer research , biology , genus
Malignant melanoma metastases to regional lymph nodes may be mimicked by several non‐neoplastic processes, including sinus histiocytosis induced by fragments shed from joint prostheses. A patient who had an elective lymph node dissection for malignant melanoma and was found to have “post‐prosthesis lymph node histiocytosis” resembling metastatic disease is described. Knowledge of the patient's past history of a total shoulder joint replacement along with the use of polarized light microscopy to identify birefringent particles of prosthetic debris allows for an accurate histologic diagnosis. © 1995 Wiley‐Liss, Inc.