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Lymph node cancer of the mediastinal or hilar region with an unknown primary site
Author(s) -
Kohdono Satoshi,
Ishida Teruyoshi,
Fukuyama Yasuro,
Hamatake Motoharo,
Takenoyama Mitsuhiro,
Tateishi Masahiro,
Sugimachi Keizo
Publication year - 1995
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930580311
Subject(s) - medicine , lymph node , mediastinal lymph node , lymph , cancer , lung cancer , pathological , carcinoma , radiology , mediastinum , primary tumor , pathology , metastasis
We herein report three cases of lymph node cancer of the mediastinal or hilar region, in which the primary sites could not be determined in spite of performing various systemic examinations. Two cases revealed a large cell anaplastic carcinoma in the mediastinal lymph node, while the other demonstrated a small cell carcinoma in the hilar lymph node. However, based on radiographic and pathological examinations, the primary sites could not be found in either the head and neck, lung, or abdominal organs. All cases underwent surgical resections for lymph node cancer, while two patients also received adjuvant therapy. Two patients experienced recurrence soon after treatment. Despite the rarity of this disease, lymph node cancer must always be kept in mind when an enlargement of either the mediastinal or hilar lymph node is detected in patients with an unknown primary site, and a poor prognosis is generally expected. © 1995 Wiley‐Liss, Inc.