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Lipid peroxidation product in bile from patients with carcinoma of the gallbladder: A preliminary study
Author(s) -
Shukla Vijay K.,
Shukla Prabhat K.,
Pandey Manoj,
Rao Balaji R.,
Roy Salil K.
Publication year - 1994
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930560415
Subject(s) - lipid peroxidation , gall , gallbladder , medicine , carcinoma , gastroenterology , cholecystectomy , 4 hydroxynonenal , oxidative stress , biology , botany
Samples of gall bladder bile from patients with and without carcinoma of the gallbladder were examined for lipid peroxidation (free radical oxidation) products. 4‐hydroxynonenal (HNE) was found in higher concentration in the bile of patients with carcinoma of the gall bladder. There was also a highly significant difference in the concentration of HNE among carcinoma of the gall bladder, cholelithiasis and control group of patients with miscellaneous abdominal disorders. This is the first study of lipid peroxidation in carcinoma of the gall bladder. © 1994 Wiley‐Liss, Inc.