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Histogenesis of small colonic adenocarcinomas
Author(s) -
Rubio Carlos,
Shetye Jayant,
Jaramillo Edgar
Publication year - 1994
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930560114
Subject(s) - histogenesis , adenocarcinoma , medicine , adenoma , lesion , pathology , cancer , immunohistochemistry
It has been claimed that in order to identify the type of mucosal lesion which precedes colonic adenocarcinoma only those tumours measuring ⩽1 mm in diameter should be considered. The review of the English literature indicates that only 35 colorectal adenocarcinomas measuring ⩽1 cm in diameter have been so far reported. From the three cases of colonic adenocarcinoma measuring 8 mm or less in diameter presented here, one adenocarcinoma originated in a flat adenoma, the second in an exophytic tubular adenoma, and the third showed no adenomatous component. It would thus appear that colonic adenocarcinomas can originate not only from exophytic adenomas or from flat adenomas but also from apparently nonadenomatous flat mucosa. © 1994 Wiley‐Liss, Inc.