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Gastric cancer in young adults: Growth accelerating effect of pregnancy and delivery
Author(s) -
Furukawa Hiroshi,
Iwanaga Takeshi,
Hiratsuka Masahiro,
Imaoka Shingi,
Ishikawa Osamu,
Kabuto Toshiyuki,
Sasaki Yo,
Kameyama Masao,
Ohigashi Hiroaki,
Nakamori Shoji
Publication year - 1994
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930550103
Subject(s) - medicine , cancer , pregnancy , obstetrics , young adult , gynecology , biology , genetics
The relationship between pregnancy and/or delivery (p&d) and the stage of gastric cancer was studied in 64 female and 57 male patients aged 34 or younger with gastric cancer. Gastric cancer diagnosed within 2 years after p&d (group A, 20 patients) was more progressive (unresectable in 20%) than those of the other young female patients with children (group B, 24 patients; 5%) or without children (group C, 20; 0%), or young male patients (group D, 57; 3%) ( P < 0.05). The 5‐year survival rate in group A (60.0%) was lower than in group B (83.3%) and group C (85.0%) ( P < 0.05 between groups A and B). There were no differences in the duration from the onset of subjective symptoms to diagnosis in the four groups. Out of eight patients who were pregnant after gastrectomy for stomach cancer, one died from recurrence immediately after abortion. These results suggest that pregnancy and/or delivery in young females accelerates the growth of stomach cancer. © Wiley‐Liss, Inc.