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Response with combined modality treatment in childhood rhabdomyosarcoma
Author(s) -
Raje Noopur S.,
Rao Suchitra R.,
Vaidya Sucheta J.,
Shah Rajesh V.,
Nair Chandrika N.,
Pai Suresh K.,
Kurkure Purna A.,
Pande Subodhchandra C.,
Desai Prafulla B.,
Advani Suresh H.
Publication year - 1993
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930540411
Subject(s) - medicine , rhabdomyosarcoma , modality (human–computer interaction) , treatment modality , childhood cancer , oncology , sarcoma , cancer , pathology , artificial intelligence , computer science
Abstract Children diagnosed with rhabdomyosarcoma at the Tata Memorial Hospital during the period January 1986‐December 1988 were studied. All were treated with combination chemotherapy incorporating vincristine, Adriamycin, and cyclophosphamide given sequentially in repeated cycles over 18 months, along with local radiotherapy. Of 24 patients, 18 patients had advanced‐stage disease at onset. All patients have been followed up for 18 months or more. Of the 11 patients with group III disease, six are in complete remission; of the six patients with group IV disease, two patients are in complete remission. These results are clearly better than those achieved in the past, where surgery was employed as the primary modality of therapy with chemoradiotherapy given only for patients with group IV disease. © 1993 Wiley‐Liss, Inc.