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Merkel cell carcinoma: Report of two cases and clinical considerations
Author(s) -
Magrini Stefano M.,
Bianchi Simonetta,
Mungai Valiano,
Biti Gianpaolo
Publication year - 1992
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930490215
Subject(s) - medicine , merkel cell carcinoma , radiation therapy , distant metastasis , pathological , carcinoma , neoplasm , merkel cell , presentation (obstetrics) , surgery , metastasis , dermatology , radiology , cancer , pathology
We present the clinical and pathological features of two cases of facial Merkel cell carcinoma (MCC) and a critical reappraisal of the literature on this subject. Among patients with this presentation of a rare neoplasm, the disease is very often localized (local or locoregional growth, without distant metastases). Radiotherapy seems to be highly effective in obtaining local control and possibly cure, even when used as the sole treatment method; prompt regression of the neoplastic masses has been observed in both the cases we treated. One of them, and many of those reported in the literature and treated with radiotherapy alone or combined with surgery, achieved long‐term survival.