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Elevated serum gastrin levels in patients with gastric cancer
Author(s) -
Rakic Srdjan,
Hinder Ronald A.,
Adanja Gordana,
Demeester Tom R.
Publication year - 1991
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930470204
Subject(s) - medicine , cancer , gastrin , gastroenterology , oncology , secretion
Elevated plasma gastrin levels have been found in patients with colorectal cancer. We measured fasting serum gastrin levels in control subjects (n = 12), patients with gastric cancer (n = 43), and patients with carcinoma of the esophagus (n = 55). Serum gastrin levels were significantly higher in patients with gastric cancer compared to normal controls ( P < 0.005) and those with esophageal cancer ( P < 0.05). This information may add to our understanding of the pathogenesis of gastric cancer.