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Leukocyte alkaline phosphatase score in patients with cerebrovascular disease and in patients with primary and metastatic brain tumors
Author(s) -
Walach Natalio,
Guterman Amiram,
Rabinowitz Haim,
Kaufman Suzana,
Habot Beni
Publication year - 1991
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930460109
Subject(s) - medicine , alkaline phosphatase , primary (astronomy) , oncology , disease , enzyme , biochemistry , chemistry , physics , astronomy
Leukocyte alkaline phosphatase (LAP) activity in peripheral blood was determined in 54 patients with cerebrovascular disease (CVD), 11 patients with primary brain tumor, and 23 patients with metastatic brain tumor. The LAP score of the primary brain tumor patients (155 ± 40) was significantly higher ( P <0.03) than the LAP score for cerebrovascular disease patients (96 ± 87). The LAP score levels of the metastatic brain tumor patients (251 ± 55) was significantly higher as compared with both the cerebrovascular disease ( P <0.001) and primary brain tumor groups ( P <0.001). The LAP score could serve as an additional, although non‐specific, marker to assist in the differentiation between cerebrovascular disease and brain tumors.