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Phyllodes tumor of the breast: A clinicopathologic study of 34 cases
Author(s) -
Kario Kazuomi,
Maeda Sakan,
Mizuno Yoshifuml,
Makino Yoshihiko,
Tankawa Hidemitsu,
Kitazawa Souhei
Publication year - 1990
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930450111
Subject(s) - medicine , phyllodes tumor , pleomorphism (cytology) , pathological , pathology , stromal cell , immunohistochemistry
Thirty‐four cases of phyllodes tumor of the breast were studied to evaluate the clinical and pathological features, which correlate with local recurrence. Histologically, local recurrence correlated with the finding of more than ten mitotic figures per ten high‐power fields, marked cellularity, prominent nuclear pleomorphism, and stromal overgrowth. Older patients and patients with larger tumors had a higher probability of local recurrence. Stromal overgrowth correlated with the other histological parameters, with rapid tumor growth, a tumor diameter of over 10 cm, and with local recurrence. It was thus considered to be a histological indicator of the malignant potential of phyllodes tumor of the breast.