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Pancreatic somatostatinoma: A case report and review of the literature
Author(s) -
Konomi Kohki,
Chijiiwa Kazuo,
Katsuta Toshiro,
Yamaguchi Kohji
Publication year - 1990
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930430414
Subject(s) - medicine , splenectomy , synaptophysin , anorexia , malaise , pancreas , diabetes mellitus , gastroenterology , immunohistochemistry , splenic flexure , pancreatectomy , somatostatin , insulinoma , endocrinology , cancer , colonoscopy , colorectal cancer , spleen
A 56‐year‐old man underwent distal pancreatectomy, splenectomy, and partial resection of the splenic flexure of the colon because of tumor in the tail of pancreas and the splenic hilus. The patient presented with symptoms of general malaise, anorexia, weight loss, mild diarrhea, and borderline diabetes mellitus, although there was no cholelithiasis. The diagnosis remained unclear until immunohistochemical studies of the resected specimen revealed somatostatin and synaptophysin, suggesting a somatostatinoma. Twenty‐three reported cases of pancreatic somatostatinoma are reviewed and their clinical features discussed. The role of immunohistochemical studies in the diagnosis of somatostatinoma is described.