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Observations on Indian node‐negative breast cancer patients: A multivariate analysis
Author(s) -
Vyas J. J.,
Desai P. B.,
Sampat M. B.,
Shinde S. R.,
Rao D. N.,
Sarkar Sudeep,
Badwe Rajan,
Tiwari J.,
Koppikar A.
Publication year - 1989
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930420411
Subject(s) - medicine , multivariate analysis , breast cancer , multivariate statistics , oncology , cancer , gynecology , demography , statistics , mathematics , sociology
The modern treatment of breast cancer has evolved over the past 100 years based on clinical observations. Therapeutic principles, from the choice of surgical procedure to the management of disseminated disease, have also changed. The axillary tumour burden, that is, the number of histologically positive nodes (N + ) plays an important role as a prognostic factor. However, in histologically Negative nodes (N − ), it is necessary to discriminate individuals at high risk despite negative nodes. This presentation analyses retrospectively the prognostic factors for long‐term failures in N − patients. These prognostic factors need to be studied in detail, and controlled clinical trials should be carried out to detect high risk N − patients and consider them for adjuvant chemotherapy.