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The use of a hand‐held gamma detector improves the safety of isolated limb perfusion
Author(s) -
Sardi Armando,
Minton John Peter,
Mojzisik Cathy,
Nieroda Carol A.,
Ferrara Peter J.,
Hinkle George H.,
Thurston Marlin O.,
Martin Edward W.
Publication year - 1989
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930410308
Subject(s) - medicine , perfusion , nuclear medicine , thigh , gamma camera , leakage (economics) , technetium 99m , surgery , radiology , scintigraphy , economics , macroeconomics
We used two hand‐held gamma‐detecting probes (GDP) (Neoprobe™ 1000 system) capable of detecting small gamma emissions to monitor leakage in patients undergoing hyperthermic isolated limb perfusion (HILP) who received 800 μCi Technetium 99m pentetate through the perfusate. The percentage of gamma‐ray leakage was calculated by a simultaneous reading of two probes at 1‐minute intervals (one over the precordial area and one over the thigh) and this was compared to results of simultaneous blood sampling from the perfusate and systemic circulation at 15‐minute intervals for gamma well counting (GWC). The percentage of leakage recorded by the GDPs was essentially identical to that detected by the GWC (7.3% and 8.2%, respectively at the conclusion of the perfusion). The GDP gives an immediate and accurate indication of the percentage of leakage during HILP, making it a safer procedure.