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Metastatic extramammary Paget's disease: Dramatic response to combined modality treatment
Author(s) -
Balducci Lodovico,
Athar Mohammad,
Smith George F.,
Khansur Tawfiq,
McKenzie David,
Crawford E. David
Publication year - 1988
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930380111
Subject(s) - medicine , extramammary paget's disease , scrotum , histogenesis , disease , radiation therapy , chemotherapy , lesion , dermatology , treatment modality , pathology , radiology , surgery , immunohistochemistry
A case of extramammary Paget's disease is reported. The distinguishing features of the case are: (1) localization of the primary lesion to the scrotum, (2) development of metastases in the absence of a recognizable underlying carcinoma, and (3) response of the systemic disease to a combination of radiation therapy and chemotherapy. The histogenesis, clinical behavior, and treatment of extramammary Paget's disease are reviewed.