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Pyridoxine: A potential local antidote for mitomycin‐C extravasation
Author(s) -
Rentschler Robert,
Wilbur David
Publication year - 1988
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930370412
Subject(s) - extravasation , medicine , antidote , pyridoxine , mitomycin c , necrosis , tissue necrosis , anesthesia , pharmacology , surgery , pathology , toxicity
Two cases are presented which suggest that pyridoxine injected into a Mitomycin‐C extravasation site may slow or prevent necrosis, and may decrease the pain associated with the chronic ulceration of extravasation.