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Evaluation of N‐acetylneuraminic acid, carcinoembryonic antigen, and alpha‐fetoprotein as markers for advanced carcinoma
Author(s) -
Khanderia Ujjaini,
Grossman H. Barton
Publication year - 1988
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930370411
Subject(s) - carcinoembryonic antigen , medicine , alpha fetoprotein , oncofetal antigen , sialic acid , n acetylneuraminic acid , carcinoma , colorectal cancer , antigen , gastroenterology , oncology , pathology , cancer , immunology , tumor associated antigen , hepatocellular carcinoma , biochemistry , biology , immunotherapy
Sialic acid (N‐acetylneuraminic acid, NANA), carcinoembryonic antigen (CEA), and alpha‐fetoprotein (AFP) were measured in a group of patients with advanced carcinoma (primarily colorectal). The percent change of NANA was less than that with CEA, and more reliably separated patients with stable disease from those with tumor regression or progression. AFP was a good predictor of clinical course in the few patients in which it was measured.