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Regression analyses of prognostic factors in colorectal cancer
Author(s) -
Hannisdal Einar,
Thorsen Glen
Publication year - 1988
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930370209
Subject(s) - medicine , colorectal cancer , leukocytosis , stage (stratigraphy) , proportional hazards model , oncology , multivariate analysis , erythrocyte sedimentation rate , gastroenterology , multivariate statistics , survival analysis , cancer , paleontology , biology , statistics , mathematics
In a follow‐up study of 110 patients with colorectal cancer, age, sex, erythrocyte sedimentation rate (ESR), hemoglobin (Hb), leukocyte count, emergency operation, tumor site, Dukes' stage, and histologic grade were tested in survival analyses. Dukes' stage was a highly superior prognostic discriminator. In multivariate survival analysis (Cox model) elevated ESR and leukocytosis were significant prognostic factors in addition to the Dukes' stage, indicating high‐risk patients with shorter survival.