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A genetic influence on alveolar cell carcinoma
Author(s) -
Paul Sindy M.,
Bacharach Benjamin,
Goepp Carla
Publication year - 1987
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930360407
Subject(s) - sibling , medicine , carcinoma , oncology , trait , pathology , developmental psychology , psychology , computer science , programming language
Abstract Analysis of three siblings with alveolar carcinoma is presented. HLA markers were performed on the index cases and on a normal sibling control. The three affected patients shared HLA‐A 28, which was absent in the control sibling. A familial recessive trait may have contributed to the development of alveolar cell carcinoma in this family. This family represents the first reported group of three siblings with alveolar carcinoma.