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Postoperative active specific immunotherapy with supportive measures in patients suffering from recurrent metastasized melanoma: Case reports of six patients
Author(s) -
Tallberg T.,
Kalima T.,
Halttunen P.,
Tykkä H.,
Mahlberg K.,
Matous B.,
Sundell B.
Publication year - 1986
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930330213
Subject(s) - medicine , immunotherapy , melanoma , active immunotherapy , oncology , metastatic melanoma , cancer , cancer research
The clinical results from postoperative active specific immunotherapy using autologous polymerized tumor material in six patients suffering from metastasized melanoma is reported. Correction of an alleged systemic deficiency leading to malignant cell transformation was attempted by administrating certain essential trace elements, amino acids, vitamins, and a diet containing lipids, extracted from the mammalian central nervous system, after heating. Vaccinations against influenza were also given as a precaution against certain viral infections sometimes seen to precede melanoma recurrence. The clinical results with this postoperative adjuvant therapy are so encouraging that we suggest that sterile tumor tissue should be saved at operation and treated to produce insoluble particles as an option for postoperative treatment of patients suffering from metastasized melanoma. Prospective randomized studies are indicated.