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Cholecystitis secondary to infusion chemotherapy
Author(s) -
Pietrafitta Joseph J.,
Anderson Bernhard G.,
O'Brien Michael J.,
Deckers Peter J.
Publication year - 1986
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930310413
Subject(s) - medicine , cholescintigraphy , complication , gallbladder , chemotherapy , floxuridine , surgery , cholecystitis , colorectal cancer , acute cholecystitis , general surgery , cancer , fluorouracil
This report centers on a patient with metastatic colorectal cancer who developed acute and chronic cholecystitis secondary to the infusion of FUDR (fluoro‐deoxyuridine) into the hepatic artery. This was documented by sonography, cholescintigraphy, and, ultimately, pathologically on the surgically removed specimen. Undoubtedly, with increasing cumulative treatment days made possible through technological advances in delivery systems, this complication will be seen more frequently. Prophylactic removal of the gallbladder, at the time of pump placement, which does not significantly prolong the operative time nor increase the operative mortality, should be performed to prevent this complication from occurring.

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