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A misleading flow cytometric analysis of dna in an adenocarcinoma: A comparative flow cytometric and cytogenetic study
Author(s) -
Lee Greta M.,
Youngberg George A.
Publication year - 1986
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930310411
Subject(s) - adenocarcinoma , flow cytometry , pathology , medicine , cytogenetics , biopsy , population , dna , chromosome , biology , cancer , genetics , immunology , gene , environmental health
A case is presented in which flow cytometric and cytogenetic analysis was done on a biopsy from a highly anaplastic metastatic adenocarcinoma. Flow cytometric analysis of DNA content failed to show a significant population of aneuploid cells. However, histologic examination revealed a substantial number of tumor cells, and cytogenetic analysis produced chromosome counts ranging from 20 to 144.