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Cervical lymph node metastases of oral carcinoma related to the depth of invasion of the primary lesion
Author(s) -
Thompson Stevan H.
Publication year - 1986
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930310209
Subject(s) - medicine , tongue , lamina propria , lesion , pathology , cervical lymph nodes , carcinoma , pathological , metastasis , lymph node , infiltration (hvac) , tongue neoplasm , cancer , epithelium , physics , thermodynamics
Squamous cell carcinoma of the tongue has been found to have a greater frequency of cervical metastases on initial examination than lesions affecting other oral sites. This study analyzes a sample of 21 pathological specimens of oral carcinoma and block neck dissections relating the confirmed historical presence of cervical metastasis to the depth of invasion of the primary lesion. Tongue carcinomas were compared with lesions affecting other oral sites. An arbitrary anatomical levelling system was devised to assess the depth of invasion. Tongue carcinomas show a propensity to infiltrate more deeply than lesions affecting other oral sites. For the entire sample, carcinomas infiltrating the superficial lamina pro‐pria occurred much less frequently than lesions showing a deeper infiltration pattern. Overall, lesions infiltrating the deep lamina propria do not exhibit a reduced frequency of occurrence compared to lesions infiltrating me skeletal muscle; however, carcinomas affecting other oral sites showed a reduced frequency of deeply infiltrating lesions in comparison to more superficial lesions. Carcinomas confined to the superficial lamina propria seem to have a better prognosis in relation to developing cervical metastases, and this does not appear to be influenced by age, sex, site, size or degree of differentiation.