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Common duct stricture associated with hepatic artery infusion of FUDR
Author(s) -
Laughlin Edward H.
Publication year - 1986
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930310113
Subject(s) - medicine , common hepatic duct , lesion , radiology , hypoxemia , artery , duct (anatomy) , surgery , common bile duct
A case report is presented giving the first detailed description of a benign common duct stricture occurring in a patient receiving hepatic artery infusion of FUDR for metastatic colon cancer. It is postulated that the stricture results from a combination of drug toxicity, and hypoxemia of the duct, with the lesion occurring more often than is recognized. A guide is given for the evaluation of the FUDR‐infused patient with suspected nonmalignant duct stricture, and for the methods of alleviating extrahe‐patic blockage in these individuals.