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The increase in immunosuppression and its role in the development of malignant lesions
Author(s) -
Cole Warren H.
Publication year - 1985
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930300303
Subject(s) - immunosuppression , medicine , transplantation , kidney transplantation , human immunodeficiency virus (hiv) , immunodeficiency , immunology , intensive care medicine , surgery , immune system
The first evidence that a major operation results in immunosuppression appeared in 1957. A few years later, numerous articles appeared in the medical literature showing that the same effect took place in the human being. When kidney transplantation was begun, it was soon learned that immunosuppression was necessary to obtain good results. Soon after suppression was adopted it was noted that malignancies were being encountered. The same was true with cardiac transplantation. Within the many types of immunodeficiency's, malignant lesions are significantly encountered in only one‐AIDS.