Premium
Treatment of perineural metastasis from squamous carcinoma of the skin with aggressive combination chemotherapy and irradiation
Author(s) -
Loeffler Jay S.,
Larson David A.,
Clark John R.,
Weichselbaum Ralph R.,
Norris Charles M.,
Ervin Thomas J.
Publication year - 1985
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930290310
Subject(s) - medicine , perineural invasion , radiation therapy , metastasis , head and neck , chemotherapy , skull , basal cell , carcinoma , surgery , oncology , cancer
Perineural metastasis from squamous cell carcinoma is quite rare. The treatment of such metastasis in the head and neck region is difficult due to base of skull or intracranial involvement by tumor. Surgery and radiotherapy may provide local control, but patients often fail distantly. We present a patient with squamous cell carcinoma presenting with perineural metastasis who was successfully treated with combination chemotherapy and definitive radiation therapy. Suggestions of therapeutic management are made of this uncommon clinical problem.