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Variability of heating patterns in animals by magnetic induction hyperthermia
Author(s) -
Storm F. Kristian,
Christensen Douglas A.,
Olch Arthur J.,
Silberman Allan W.,
Roe Denise J.,
Harrison William H.,
Elliott Robert S.,
Morton Donald L.
Publication year - 1985
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930290204
Subject(s) - hyperthermia , medicine , induction heating , perfusion , abdomen , heat generation , thermoregulation , electromagnetic heating , core (optical fiber) , anatomy , nuclear medicine , biomedical engineering , mechanics , radiology , thermodynamics , materials science , electromagnetic coil , composite material , physics , quantum mechanics
In a test of electromagnetic induction hyperthermia to deep viscera of a live dog model, we found that heating was not uniform to any depth, but was quite variable. In general, there was a thermal gradient between peripheral and central portions of the transposed spleen of about 1°C. Though heat generation within the abdomen was not uniform, its temperature pattern in the alive animal resulted in significant heating of that part of the organ that had been surgically placed at the center of the animal. This heating could not be explained by perfusion with regionally heated core blood. Our results indicate that extensive investigations in living systems and complex dynamic phantoms will be necessary before individual patient response can be predicted.