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Immune status in advanced upper gastrointestinal cancers
Author(s) -
Singh Gurpreet,
Das S. N.,
Khan. N.
Publication year - 1985
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930290113
Subject(s) - medicine , immune system , immune status , gastrointestinal cancer , antibody , chemotherapy , immunology , cancer , lymphocyte , immunity , gastroenterology , colorectal cancer
Thirty‐eight cases of advanced upper gastrointestinal cancer were assessed for their immune status prior to any form of therapy. Cell‐mediated immunity, as tested by absolute lymphocyte count, T‐cell count and delayed cutaneous hypersensitivity reactions to purified protein derivative and phytohemagglutinin showed severe depression. Immunoglobulins A and M were elevated, while immunoglobulin G reduced. No correlation could be established between the immune status and the site of cancer or its extent, the performance status of the patients, or their response to chemotherapy.