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Amsacrine and etoposide induced paralytic ileus in a patient with acute myelomonocytic leukemia
Author(s) -
Kucuk Omer,
Apostol James V.
Publication year - 1985
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930280305
Subject(s) - medicine , acute myelomonocytic leukemia , amsacrine , ileus , paralytic ileus , etoposide , leukemia , chemotherapy , gastroenterology , surgery , anesthesia
A 73‐year‐old man with acute myelomonocytic leukemia developed a severe paralytic ileus after amsacrine and etoposide treatment. The ileus did not respond to treatment with gastric suction and intravenous fluids. Autonomic neuropathy induced by anti‐neoplastic drugs may lead to this life‐threatening condition.