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Recurrences after irradiation in early vocal cord cancer with literature review
Author(s) -
Jose B.,
Calhoun David L.,
Mohammed Alyas
Publication year - 1984
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930270405
Subject(s) - medicine , laryngectomy , radiation therapy , surgery , cancer , stage (stratigraphy) , cord , larynx , paleontology , biology
Radiation therapy in early glottic cancer offers an excellent cure rate with preservation of voice. This study is an analysis of 25 (18%) patients who had failures after irradiation. Ten patients were in stage I (T 1 N 0 M 0 ) and 15 patients in stage II (T 2 N 0 M 0 ). All patients received megavoltage irradiation with an average dose of 6600 rad, 180 to 200 rad per day, 5 days in a week. Of the failures, 15 patients had the tumor controlled by salvage surgery, laryngectomy being the most common surgical procedure. The median time to recurrence was 23 months. A detailed analysis of the failures, along with a literature review, is done in this paper.