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Preoperative hyperthermo‐chemo‐radiotherapy effective for carcinoma of the esophagus
Author(s) -
Sugimachi Keizo,
Inokuchi Kiyoshi,
Kai Hidenobu,
Ueo Hiroaki,
Kuwano Hiroyuki,
Matsufuji Hidemasa
Publication year - 1984
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930270315
Subject(s) - medicine , esophagus , radiation therapy , carcinoma , chemotherapy , metastasis , cancer , esophageal cancer , hyperthermia , surgery , oncology
We prescribed hyperthermo‐chemo‐radiotherapy preoperatively for 13 patients with esophageal carcinoma. Viable cancer cells disappeared in four out of 13 patients, and all of these four patients survive without recurrence 3 to 34 postoperative months, at this writing. In another seven out of the 13, cancer cells were extensively damaged, despite the presence of a small number of viable cancer cells, and three out of these seven died with a recurrence. For two, the treatment was ineffective, and they died of liver metastasis and a local recurrence, respectively. These findings suggest that preoperative hyperthermia combined with chemotherapy and radiation is highly effective for treatment of carcinoma of the esophagus.