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Bacterial adherence to bladder tumors in the mouse
Author(s) -
Bagley Demetrius H.,
Velanovich Vic,
Jones Kenneth W.,
Heggers John P.
Publication year - 1983
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930230405
Subject(s) - bladder tumor , medicine , bacteria , bearing (navigation) , pathology , urology , cancer research , bladder cancer , cancer , biology , cartography , genetics , geography
Mice with intravesical urothelial tumors (MBT‐2) were challenged with E coli inoculated intravesically. Adherence of bacteria measured at 15 min or persistent infection at 24 h was significantly greater in the tumorbearing bladders than in normal non‐tumor‐bearing mice. The tumorbearing portion of the bladder contained significantly more bacteria than the non‐tumor‐bearing portion.