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Nonsteroid antiinflammatory drugs and tamoxifen for desmoid tumors and carcinoma of the stomach
Author(s) -
Waddell William R.,
Cerner Robert E.,
Reich Marshall P.
Publication year - 1983
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930220314
Subject(s) - medicine , tamoxifen , cyclophosphamide , stomach , fluorouracil , chemotherapy , oncology , gastric carcinoma , carcinoma , cancer , breast cancer
The results of treatment of desmoid tumor patients with nonsteroid antiinflammatory drugs alone or in combination with tamoxifen are described. Tumor growth was inhibited in six of seven patients. Nonsteroid antiinflammatory drugs administered along with 5‐fluorouracil and cyclophosphamide and other inhibitors of T‐suppressor cells were used to treat nine patients with metastatic carcinoma of the stomach. Survival of these patients was extended so that after 12 months minimal follow‐up the majority are well. A prospective controlled clinical trial is indicated.