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Measurement of progesterone receptor in human renal cell carcinoma and normal renal tissue
Author(s) -
McDonald Michael W.,
Diokno Ananias C.,
Seski Jan C.,
Me K. M. J.
Publication year - 1983
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930220305
Subject(s) - medicine , renal cell carcinoma , progesterone receptor , receptor , medroxyprogesterone acetate , carcinoma , cell , pathology , endocrinology , cancer , oncology , urology , breast cancer , hormone , biology , estrogen receptor , genetics
Abstract Progesterone receptor was measured in eight samples of renal cell carcinoma, nine samples of normal renal tissue, and one sample of melanoma tissue. Progesterone receptor was identified in all samples, with the exception of one renal cell carcinoma. Three patients, all with receptor‐positive tumors, were treated with medroxyprogesterone acetate for metastatic disease. In one of these patients there was a partial objective response to treatment. Further research regarding progesterone receptor in renal cell carcinoma is indicated.