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Treatment of advanced gastric cancer with 5‐fluorouracil versus mitomycin C
Author(s) -
Gupta Saroj
Publication year - 1982
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930210206
Subject(s) - medicine , mitomycin c , toxicity , fluorouracil , adenocarcinoma , stomach , stomach cancer , cancer , gastroenterology , chemotherapy , oncology , surgery
Thirty‐eight patients of advanced adenocarcinoma of the stomach were randomly administered intensive courses; of either 5‐FU or mitomycin C by intravenous route, The 5‐FU administration resulted in a slightly better response than mitomycin C, although the toxic effects of the two drugs were more or less the same. The selection of drug regime in the present study has been based on cost, availability, potential toxicity, and minimal alteration of the patients' life style.