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Villous adenomatosis and carcinoma in a 66‐year‐old man with familial polyposis
Author(s) -
Roseman James M.,
Clausen Kathryn P.,
Minton John P.
Publication year - 1982
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930200412
Subject(s) - medicine , colorectal cancer , family history , cancer , familial adenomatous polyposis , antecedent (behavioral psychology) , pathology , carcinoma , intestinal polyp , gastroenterology , psychology , developmental psychology
A patient evaluated and treated for carcinoma of the colon and multiple polyps and the patient's family represent a new pattern of clinical and pathologic manifestations of familial polyposis. The lack of antecedent family history of polyposis, the presence of diffuse villous degeneration, and the occurrence of cancer at age 66 years are a departure from the usual character of this syndrome. Subsequent generations continued the expression of familial polyposis with prominent villous changes. New insight into a possible relationship among the various types of polyps as well as between them and cancer is suggested by this family.