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Steroid receptors in tumors of nerve sheath origin
Author(s) -
Chaudhuri Prabir K.,
Walker Michael J.,
Das Gupta Tapas K.,
Beattie Craig W.
Publication year - 1982
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930200403
Subject(s) - receptor , medicine , steroid , cytosol , soft tissue , pathology , nerve sheath , endocrinology , biology , schwannoma , hormone , enzyme , biochemistry
Abstract The present study dearly demonstrates that neurofibromas and neurofibrosarcomas are devoid of cytosol receptor for steroid. These observations are in sharp contrast to the significant incidence of receptors in soft tissue and osseous sarcomas and raise doubts that steroids exert a direct effect on the growth of these tumors.