Oat cell carcinoma of the esophagus | Zendy

Sarma Deba P. | Zendy

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Oat cell carcinoma of the esophagus

Author(s) -

Sarma Deba P.

Publication year - 1982

Publication title -

journal of surgical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.201

H-Index - 111

eISSN - 1096-9098

pISSN - 0022-4790

DOI - 10.1002/jso.2930190307

Subject(s) - oat cell carcinoma , esophagus , medicine , carcinoma , adenocarcinoma , pathology , enterochromaffin cell , basal cell , cell , cancer , biology , respiratory disease , lung , receptor , serotonin , genetics

An oat cell carcinoma occurring in the esophagus of a 59‐year‐old man is described. A review of another 22 cases of such a tumor from the English literature is made. These tumors may have three histologic patterns: pure oat cell carcinoma, oat cell carcinoma with squamous cell carcinoma, and oat cell carcinoma with adenocarcinoma. They appear to arise from enterochromaffin cells; the neoplastic cells show argyrophilia and neurosecretory‐type granules on electron microscopy. Resection has been the principal mode of therapy. Overall survival for these patients is about 6 months, with most patients dying of extensive metastatic disease.

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