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Long‐term remission of an advanced head and neck tumor following intra‐arterial infusion with cis‐dicholordiammine platinum
Author(s) -
Horn Yoav,
Adam Yehuda,
Walach Natalio,
Ilian Mahmoud
Publication year - 1981
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930180213
Subject(s) - medicine , head and neck , chemotherapy , radiation therapy , complete remission , head and neck cancer , surgery , basal cell , head and neck squamous cell carcinoma
A 65‐year‐old man with squamous cell carcinoma of the head and neck was initially treated with radiation therapy and systemic chemotherapy resulting in a complete remission. Recurring tumor, 2½ years later, caused advanced destruction of most left hemi‐face tissues. Intraarterial infusion with cis‐dichlorodiammine platinum (CDDP) to a total dose of 125 mg resulted in a complete remission of 15 months duration. The value of the use of the intra‐arterial route in treating advanced head and neck tumors with CDDP is discussed.