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Surgical treatment of locally far‐advanced lung carcinoma
Author(s) -
Takita Hiroshi,
Edgerton Francis,
Conway Donna,
Marabella Patrick C.,
Vincent Ronald G.
Publication year - 1981
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930170311
Subject(s) - medicine , lung cancer , surgery , lung , radiation therapy , carcinoma , chemotherapy , stage (stratigraphy) , adjuvant , immunotherapy , survival rate , oncology , cancer , paleontology , biology
Abstract It has been our policy to employ radical lung resection as a primary treatment whenever possible in locally far‐advanced lung cancer. In order to assess the therapeutic results, a total of 132 patients with locally far‐advanced lung cancer who had radical lung resection were reviewed. Postoperative mortality was 10%. A significant difference in survival was seen between those patients receiving no adjuvant therapy, radiation or single agent chemotherapy and those receiving cis‐platinum‐based polychemotherapy and/or immunotherapy (respective median survivals 14.25 and 25.68 months, P <0.05 Breslow test of failure rates). Aggressive surgery followed by effective adjuvant therapy in locally far‐advanced Stage III lung carcinoma appears to produce acceptable survival results.