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Serum β 2 —microglobulin and carcinoembryonic antigen in patients with gastric disorders
Author(s) -
Satake Katsusuke,
Kitamura Teruo,
Ishikawa Tetsuro,
Mukai Ryuichiro,
Yoshimoto Takayuki,
Chung YongSuk,
Umeyama Kaoru
Publication year - 1981
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930170305
Subject(s) - carcinoembryonic antigen , beta 2 microglobulin , medicine , radioimmunoassay , gastric carcinoma , gastroenterology , carcinoma , pathology , cancer
A comparative study of carcinoembryonic antigen (CEA) and β 2 ‐microglobulin in serum was made by radioimmunoassay in 121 patients with gastric disease. There was no statistical difference in serum CEA and β 2 ‐microglobulin in patients with benign gastric disease, early gastric carcinoma, and advanced gastric carcinoma. However, CEA levels in patients with advanced gastric carcinoma were higher than those in benign gastric disease and in early gastric carcinoma but β 2 ‐microglobulin did not show any differences. Furthermore, after total removal of the tumor, the elevated CEA levels decreased but β 2 ‐microglobulin remained unchanged. We concluded that CEA appeared to predict tumor behavior more accurately in patients with gastric carcinoma than β 2 ‐microglobulin.