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Retroperitoneal sarcomas: A reappraisal of treatment
Author(s) -
Storm F. Kristian,
Eilber Frederick R.,
Mirra Joseph,
Morton Donald L.
Publication year - 1981
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930170102
Subject(s) - medicine , malignancy , sarcoma , chemotherapy , incidence (geometry) , surgery , resection , radiology , adjuvant chemotherapy , surgical resection , cancer , pathology , physics , breast cancer , optics
Retroperitoneal sarcoma, regardless of the histopathologic grade of malignancy, has a high incidence of local recurrence that is usually fatal. Surgical resection is mandatory and resectability may be improved by a midline transabdominal approach. However, even with total tumor excision, recurrence is high. A preliminary study, combining resection and preoperative adriamycin, found to be effective for established disease, suggests potentially improved prognosis. Further clinical trials employing surgery combined with adjuvant chemotherapy are warranted.