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Immunoperoxidase staining for carcinoembryonic antigen in colonic carcinoma, osteosarcoma, and chordoma
Author(s) -
Harrowe David J.,
Taylor Clive R.
Publication year - 1981
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930160102
Subject(s) - carcinoembryonic antigen , medicine , immunoperoxidase , chordoma , osteosarcoma , pathology , adenocarcinoma , positive staining , carcinoma , colonic carcinoma , staining , antibody , monoclonal antibody , cancer , immunology
Abstract An indirect immunoperoxidase method was used in an attempt to detect carcino‐embryonic antigen (CEA) in 17 well‐differentiated colonic adenocarcinomas, five osteosarcomas, and four chordomas. Fifteen of the adenocarcinomas were positive, and five of them had been fixed and embedded in 1952 and one in 1942. Two other adenocarcinomas from 1942 were not positive. CEA was not demonstrated in any of the osteosarcomas or chordomas.