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Anaplastic Carcinoma of the Thyroid in a Population Irradiated for Hodgkin Disease, 1910–1960
Author(s) -
Gétaz E. Paul,
Shimaoka Katsutaro
Publication year - 1979
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930120213
Subject(s) - medicine , anaplastic carcinoma , thyroid carcinoma , thyroid , oncology , disease , carcinoma , population , pathology , environmental health
Post‐irradiation carcinoma of the thyroid is usually histologically well‐differentiated. In general, those subjects who developed carcinoma had been exposed to low‐to‐moderate doses of irradiation for benign conditions. We reviewed the charts of 520 patients with Hodgkin's disease seen at Roswell Park Memorial Institute, and found 2 cases of anaplastic carcinoma amongst other thyroidal abnormalities. The existing reports of post‐irradiation carcinoma are reviewed and suggestions are made for the management of heavily irradiated, potentially cured patients with Hodgkin's disease.