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Long‐term survival with thorotrast cervical granuloma
Author(s) -
Lung Richard J.,
Harding Robert L.,
Herceg Stephen J.,
Schantz John C.,
Miller Stephen H.
Publication year - 1978
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.2930100209
Subject(s) - thorotrast , medicine , thorium dioxide , extravasation , malignancy , angiography , radiology , granuloma , incidence (geometry) , surgery , nuclear medicine , pathology , chemistry , physics , optics , nuclear chemistry
Thorium dioxide, a radioactive contrast material, was commonly used for cerebral angiography prior to recognition of its radiation hazard. Extravasation of the material into the extravascular tissue in the neck results in granuloma formation, thorotrastoma, long‐term morbidity, and an increased incidence of benign and malignant tumors. We report our experience with the management of 2 patients who underwent cerebral angiography with thorotrast more than 25 years ago. Aggressive surgical excision of involved tissue is warranted to ameliorate symptoms and diminish the risk of malignancy.